Receptor Grade IGF-1 LR3

Receptor Grade IGF-1 LR3 Peptide

Insulin-like Growth factor-1, or IGF-1, is a naturally produced protein with 70 amino acids. Receptor Grade IGF-1 LR3 is a synthetic variant of the naturally occurring IGF-1, which contains an extended N-terminal structure of 13 amino acids and a replacement of the glutamic acid at residue 3 with arginine. Hence, it is named IGF-1 Long R3.

Receptor Grade IGF-1 LR3

Owing to the altered structure, Receptor Grade IGF-1 L-R3 has been suggested to have increased affinity and increased anabolic potential while also binding less to IGF-1 binding proteins (IGF-1BPs). Structurally similar to insulin, this IGF-1 LR3 has the potential primarily to regulate cell tissue growth and development.

This potential has been evaluated in cell growth studies, throughout which researchers first prompted the need for developing this high-potency variant. Moreover, the classification of Receptor Grade refers to the purity of the material, which is considered higher than Media Grade IGF-1 LR3.